1 in 50 children are diagnosed with a peanut allergy1

Peanut Allergy Is The Most Common Food Allergen In Children1,2

Peanuts are the most common food allergen among children in the United States,1,2 and the #1 known cause of food-related allergic reactions.3 More than half of allergic reactions to peanuts are reported as severe in children.1 In fact, peanut allergy is a leading cause of fatalities due to food-related severe reactions.4

Navigating the complex world of peanut allergy with proper avoidance, constant vigilance, and immediate access to epinephrine is a constant challenge for families and their children.5

80% of these children will not outgrow their peanut allergy, resulting in a life-long burden5,8,9

1.5 million children in the U.S have a diagnosed peanut allergy
Allergy IQ logo

How much would you estimate the prevalence of peanut allergy has increased in your practice over the past 5 to 10 years?

16% chose 0% - 20%
17% chose 21% to 50%
56% chose 51% to 80%
11% chose >80%

Diagnoses of peanut allergy more than tripled in children from 1997 to 2008, and prevalence continues to increase.10,11

References

ANY PATIENT WITH PEANUT ALLERGY MAY BE AT RISK FOR A SEVERE REACTION1

Severity of Past Reactions Cannot Predict Severity of Future Reactions1

Peanut allergy reactions are unpredictable.1 The severity of your patient’s reaction cannot always be accurately predicted by allergen-specific immunoglobulin E (IgE) levels.1 And regardless of specific peanut protein sensitizations, severe reactions can occur.1 The child may experience an IgE- or non—IgE-mediated reaction with symptoms ranging from mild pruritus to delayed gastrointestinal symptoms to severe life-threatening reactions.2

Many factors contribute to the unpredictability of allergic reactions to peanuts. Some are1,3:

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    IgE profile—influences degree of sensitization at time of allergen ingestion1
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    Allergen—affects severity based on amount ingested, food form (cooked, raw, processed), and coingestion of other foods1
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    Dose—amount ingested affects severity of reaction1
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    Infection—affects rapidity of allergen absorption in patients1,3,4
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    Asthma—affects rapidity of allergen absorption1
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    Exercise—when associated with ingestion, affects rapidity of absorption1
References

TRACE AMOUNTS OF PEANUT POSE A RISK OF SEVERE LIFE-THREATENING REACTIONS1-4

Everyday Life Creates Multiple Risks for Unexpected Exposure to Peanuts5

Even with constant vigilance, your patients cannot always avoid exposure to peanut protein.6 In the home, unregulated and non-standardized food package labels may not always alert parents to potential cross-contact.7,8 Outside the home, patients face even greater risks.7,9 Restaurants don’t always provide food allergen information,1,7,8 and schools or homes of friends and relatives may not provide food-safe environments.7,9

Allergy IQ logo

Which environments seem to create the most risk of accidental exposure for your patients?

19% chose School
15% chose Homes of friends and relatives
63% chose Restaurants
3% chose Other

Avoidance is not foolproof.11 Accidental exposure still happens despite your patients’ best efforts.6,9

A medical chart study of children with peanut allergy (n=140) revealed10:

39% of children were accidently exposed to peanuts after their peanut allergy diagnosis within 12.5 months

Risk of trace amounts1-4:

Diagram of trace amounts of peanut that can cause severe, life-threatening reactions when accidentally ingested Diagram of trace amounts of peanut that can cause severe, life-threatening reactions when accidentally ingested
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How soon after initial diagnosis do you see accidental exposure in your patients?

16% chose Within 6 months
13% chose Within 12 months
66% chose Within 18 months
5% chose Within 24 months

It’s important to regularly ask your patients about accidental exposure frequency—no matter how mild the reactions have been.12

References

PEANUT ALLERGY IS NEVER OUT OF SIGHT, OUT OF MIND1,2

A Constant Source of Anxiety and Uncertainty for Patients and Parents1,2

The burden of peanut allergy on patients and their families goes beyond just the physical burden of avoidance and constant vigilance.1,2 It also may take an emotional toll, leaving a negative impact on the psychosocial well-being of patients and their families.1,3 In a recent survey of parents of children with peanut allergy, 73% were most concerned about accidental exposure in their kids’ daily lives.4

In a 2017 DBV Technologies sponsored survey5:

60 percent icon

report increased stress

67 percent icon

believe their child’s allergy makes it harder to be a parent

Stress and emotional burdens often impact the overall health of patients.1 Studies demonstrate that fear of allergic reactions may lead to increased anxiety and decreased quality of life for patients and parents.1,3

 

National survey sponsored by DBV Technologies in 2017 among 500 parents, 300 Healthcare Professionals (Allergists, Pediatricians, and Physician Assistants/Nurse Practitioners), and 200 educators (School Nurses & Teachers) to understand awareness, attitudes, and daily impacts related to living with peanut allergy in children ages 3-14.

The reality is that the lives of your patients and their parents are measurably different — more stressful, anxious, and challenging than the daily lives of their peers — because of peanut allergy.1,3,5

Learn more about the impact of peanut allergy on families

Learn more
Allergy IQ logo

How often do parents of children with peanut allergy tell you they feel stressed from trying to protect their children from peanut exposures and worrying about severe reactions?

15% chose Every office visit
9% chose Most office visits
73% chose Some office visits
3% chose Never

In the 2018 DBV Technologies sponsored survey, 74% of parents said they worried about being perceived as overprotective by other parents.5

References

References

  • 1. Gupta RS, Springston EE, Warrier MR, et al. The prevalence, severity, and distribution of childhood food allergy in the United States. Pediatrics. 2011;28(1):e9-e17.
  • 2. Mahdavinia M, Fox SR, Smith BM, et al. Racial differences in food allergy phenotype and health care utilization among US children. J Allergy Clin Immunol Pract. 2017;5(2):352-357.
  • 3. Blue Cross Blue Shield Association. The health of America: childhood allergies in America. Available at: https://www.bcbs.com/the-health-of-america/reports/childhood-allergies-america. Accessed August 21, 2018.
  • 4. Bock SA, Muñoz-Furlong A, Sampson HA. Fatalities due to anaphylactic reactions to foods. J Allergy Clin Immunol. 2001;107(1):191-193.
  • 5. Food Allergy Research & Education (FARE). Hope for a safer future: a special report on food allergy therapies. Available at https://www.foodallergy.org/sites/default/files/2018-06/Immuno_Report%20online.pdf. Accessed August 21, 2018.
  • 6. Data on file. 2017 Living with peanut allergy lifestyle, behavioral & psychosocial survey results. DBV Technologies. 2017.
  • 7. Organization for Economic Co-Operation and Development (OECD). OECD.Stat. Average class size 2015. Available at https://stats.oecd.org/Index.aspx?DataSetCode=EDU_CLASS. Accessed August 21, 2018.
  • 8. Neuman-Sunshine DL, Eckman JA, Keet CA, et al. The natural history of persistent peanut allergy. Ann Allergy Asthma Immunol. 2012;108(5):326-331.
  • 9. Skolnick HS, Conover-Walker MK, Koerner CB, Sampson HA, Burks W, Wood RA. The natural history of peanut allergy. J Allergy Clin Immunol. 2001;107(2):367-374.
  • 10. Sicherer SH, Muñoz-Furlong A, Godbold JH, Sampson HA. US prevalence of self-reported peanut, tree nut, and sesame allergy: 11-year follow-up. J Allergy Clin Immunol. 2010;125(6):1322-1326.
  • 11. Leickly FE, Kloepfer KM, Slaven JE, Vitalpur G. Peanut allergy: an epidemiologic analysis of a large database. J Pediatr. 2018;192:223-228.

References

  • 1. Boyce JA, Assa’ad A, Burks AW, et al. Guidelines for the diagnosis and management of food allergy in the United States: summary of the NIAID-sponsored expert panel. Nutr Res. 2011;31(1):61-75.
  • 2. Gupta RS, Springston EE, Warrier MR, et al. The prevalence, severity, and distribution of childhood food allergy in the United States. Pediatrics. 2011;28(1):e9-e17.
  • 3. Lieberman P, Nicklas RA, Randolph. C, et al. Anaphylaxis—a practice parameter update 2015. Ann Allergy Asthma Immunol. 2015;115(5):341-384.
  • 4. Shreffler WG, Baumert JL, Remingston BC, et al. The importance of reducing risk in peanut allergy: current and future therapies. Ann Allergy Asthma Immunol. 2018;120(2):124-127.

References

  • 1. Food Allergy Research & Education (FARE). Your food allergy field guide. 2017. Available at https://www.foodallergy.org/sites/default/files/migrated-files/file/field-guide.pdf. Accessed August 21, 2018.
  • 2. Allen KJ, Remington BC, Baumert JL, et al. Allergen reference doses for precautionary labeling (VITAL2.0): clinical implications. J Allergy Clin Immunol. 2014 Jan;133(1):156-164.
  • 3. Deschildre A, Elegbede CF, Just J, et al. 2016. Peanut-allergic patients in the MIRABEL survey: characteristics, allergists’ dietary advice and lessons from real life. Clin Exp Allergy. 2016;46(4):610 620.
  • 4. Schreffler WG, Baumert JL, Remingston BC, et al. The importance of reducing risk in peanut allergy: current and future therapies. Ann Allergy Asthma Immunol. 2018;120(2):124-127.
  • 5. Food Allergy Research & Education (FARE). Hope for a safer future: a special report on food allergy therapies. Available at https://www.foodallergy.org/sites/default/files/2018-06/Immuno_Report%20online.pdf. Accessed August 21, 2018.
  • 6. Neuman-Sunshine DL, Eckman JA, Keet CA, et al. The natural history of persistent peanut allergy. Ann Allergy Asthma Immunol. 2012;108(5):326-331.
  • 7. US Food and Drug Administration (FDA). Food Allergen Labeling And Consumer Protection Act of 2004 questions and answers. Updated July 18, 2006. Available at: https://www.fda.gov/Food/GuidanceRegulation/GuidanceDocumentsRegulatoryInformation/Allergens/ucm106890.htm. Accessed August 21, 2018.
  • 8. Muñoz-Furlong A, Weiss CC. Characteristics of food-allergic patients placing them at risk for a fatal anaphylactic episode. Curr Allergy Asthma Rep. 2009;9(1):57-63.
  • 9. Sicherer SH, Furlong TJ, Muñoz -Furlong A, Burks AW, Sampson HA. A voluntary registry for peanut and tree nut allergy: characteristics of the first 5149 registrants. J Allergy Clin Immunol. 2001;108(1):128 132.
  • 10. Green TD, LaBelle VS, Steele PH, et al. Clinical characteristics of peanut-allergic children: recent changes. Pediatrics. 2007;120(6):1304-1310.
  • 11. Lieberman P, Nicklas RA, Randolph. C, et al. Anaphylaxis—a practice parameter update 2015. Ann Allergy Asthma Immunol. 2015;115(5):341-384.
  • 12. Boyce JA, Assa'ad A, Burks AW, et al. Guidelines for the diagnosis and management of food allergy in the United States: report of the NIAID-sponsored expert panel. Nutr Res. 2011;31(1):61-75.

References

  • 1. Boyce JA, Assa’ad A, Burks AW, et al. Guidelines for the diagnosis and management of food allergy in the United States: report of the NIAID-sponsored expert panel. Nutr Res. 2011;31(1):61-75.
  • 2. Food Allergy Research & Education (FARE). Hope for a safer future: a special report on food allergy therapies. Available at: https://www.foodallergy.org/sites/default/files/2018-06/Immuno_Report%20online.pdf. Accessed August 21, 2018.
  • 3. Bollinger ME, Dahlquist LM, Mudd K, Sonntag C, Dillinger L, McKenna K. The impact of food allergy on the daily activities of children and their families. Ann Allergy Asthma Immunol. 2006;96(3):415-421.
  • 4. Data on file. Survey of U.S. parents of children with a peanut allergy. 2017. DBV Technologies. KRC Research.
  • 5. Data on file. 2017 living with peanut allergy lifestyle, behavioral & psychosocial survey results. DBV Technologies. 2017.